Krt5-cre
Web14 sep. 2024 · ABSTRACT. The tracheal basal cells (BCs) function as stem cells to maintain the epithelium in steady state and repair it after injury. The airway is surrounded by cartilage ventrolaterally and smooth muscle dorsally. Lineage tracing using Krt5-CreER shows dorsal BCs produce more, larger, clones than ventral BCs. Web7 mrt. 2024 · Krt5 keratin 5 [ (house mouse)] Gene ID: 110308, updated on 28-Dec-2024. Summary. Predicted to enable scaffold protein binding activity. Located in keratin …
Krt5-cre
Did you know?
WebTg(KRT5-cre/ERT2)2Ipc: Name: transgene insertion 2, I Pierre Chambon: MGI ID: MGI:2177429: Synonyms: CreERT2, K5-CreERT2, K5-Cre-ER T2, Krt5 CreERT2, … Web29 mei 2024 · H1N1 influenza virus infection induces dramatic and permanent alveolar remodeling mediated by p63+ progenitor cell expansion in both mice and some patients with acute respiratory distress syndrome. This persistent lung epithelial dysplasia is accompanied by chronic inflammation, but the driver(s) of this pathology are unknown. This work …
Web证明Krt5- (IRES-CreERT2)小鼠可以成为实现Krt阳性细胞特异性敲除或表达的工具鼠。. 图 2 Tamoxifen 诱导后，Krt5 CreERT2/+; Rosa26 tdTomato/+ 小鼠各组织中tdTomato的表达 … WebUpon tamoxifen treatment (Figure 1 B), activated CRE recombinase drives Pten deletion and expression of the enhanced yellow fluorescence protein (YFP) in K8 + luminal cells (Figure 1 C). Download : Download high-res image (3MB) Download : Download full-size image; Figure 1. Distribution of LY6D + luminal progenitor cells in PTEN-deficient ...
WebMutation details: A 14kb fragment of human keratin 5 (KRT5) promoter was used to control the expression of Cre in keratinocytes. A nuclear localization signal was added to the 5' … http://www.labmodel.cn/mod_product-view-p_id-4321.html
Web15 jul. 2002 · Tbx2, Erm, Pea3, and Pax3 are identified as downstream targets of FGF signaling in the facial area and suggest that these genes may mediate some of the effects of F GF8 during development of the nasal region. Fgf8 is required for normal development of the nasal region. Here, we have used a candidate approach to identify genes that are …
Web10 jul. 2024 · Krt5-Cre transgenic line in which Cre recombinase is driven by the HBC specific Krt5 promoter was crossed to RelA flox/flox mice to generate RelA deletion in HBCs. The Rosa26-stop flox/flox -td-Tomato strain was provided by Xinzhong Dong, Johns Hopkins Medicine. hassansinWeb图1. TdTomato的打靶策略[1] 这种鼠在正常情况下由于3×stop的存在并不能表达红色荧光，当与Cre鼠或TAM激活的CreERT2鼠交配后，产生的后代由于Cre重组酶切割loxp位点之间的序列将3×stop切除，TdTomato得到表达，就可以在Cre或CreERT2表达的组织中发出红色荧光，指示基因的位置。 hassaun valentineWebThe BK5.CreERT2 DNA construct was developed by fusing the cDNA for Cre recombinase to a mutated ligand binding domain of the human estrogen receptor (ER) resulting in … hassassian sassanWebProduction Details. Krt5-Cre;Braf f/f ;Raf1 f/f mice were generated by crossing Krt5-Cre;Braf f/f with Krt5-Cre;Raf1 f/f animals. Conditional. Yes. Conditional Description. Tissue-specific Cre expression driven by the human Keratin 5 promoter ablating both Braf and Raf1 alleles in the epidermis. Mouse Genetic Background/Cross History. hasse meinen jobWebKRT5 is part of cluster 11 Squamous epithelial cells - Epithelial cell function with confidence i Confidence is the fraction of times a gene was assigned to the cluster in repeated … hassasiyetiWeb15 aug. 2024 · Rosa26-CreERT2 小鼠种系能够通过体内他莫昔芬诱导对floxed基因表达进行时间控制。. 也就是在Rosa26位点插入了CreERT2基因使其能能够稳定表达，当进行他莫昔芬Tamoxifen给药时，Cre重组酶从细胞质进入细胞核中，作用于loxp位点从而完成条件性基因敲除。. Rosa26位点是 ... hassassinWeb21 mrt. 2024 · KRT5 (Keratin 5) is a Protein Coding gene. Diseases associated with KRT5 include Epidermolysis Bullosa Simplex 2F, With Mottled Pigmentation and Epidermolysis Bullosa Simplex 2E, With Migratory Circinate Erythema.Among its related pathways are Cell junction organization and Keratinization.Gene Ontology (GO) annotations related to this … hasse e lassale